At the age of 25, she became a professor at Hochschule fur Music in Detmold, Germany. After winning the 1st prize at the International Accordion Competition in Klingenthal, Germany and the 1st prize at the International Accordion Competition in Annecy, France, Mie Miki soon started her active performing career in Europe.

In 1989, for the first time ever as an accordionist, she was awarded the Foerderungspreis des Landes Nordrhein-Westfalen for young artists in Germany.

As a soloist, Mie Miki has appeared with renowned orchestras including the Suisse Romande Orchestra, NHK Symphony Orchestra and Belgian National Orchestra, under such conductors as Seiji Ozawa, Hiroyuki Iwaki, and Charles Dutoit.

A concert series entitled Mie Miki Accordion Works, featuring numerous premieres, takes place every year in Tokyo and more than 55 works have been dedicated to her, by composers such as Hosokawa, Hoelszky, Hespos, Huber, Ichiyanagi, Ishii and Takahashi.

More than 30 CDs have been released by companies such as Philips, Sony, Denon, etc. Currently, Ms. Miki is a professor at the Folkwang Hochschule Essen in Germany, and at the Xinjiang Arts College in China.